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Merck

SAG

S-antigen; retina and pineal gland (arrestin)

Synonyms:
RP47, S-AG
Species:
UniProtKB ID:
Gene ID:
  • Human(6295) Summary: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]
  • Mouse(20215) S-antigen, retina and pineal gland (arrestin)
  • Rat(25539) S-antigen; retina and pineal gland (arrestin)
  • fruit fly(49637) semang
  • chicken(768877) S-antigen; retina and pineal gland (arrestin)
  • dog(403906) S-antigen; retina and pineal gland (arrestin)
  • cow(280922) S-antigen; retina and pineal gland (arrestin)
  • Horse(100064951) S-antigen; retina and pineal gland (arrestin)
  • domestic cat(101100991) S-antigen; retina and pineal gland (arrestin)
  • sheep(101105037) S-antigen; retina and pineal gland (arrestin)
  • naked mole-rat(101713096) S-antigen; retina and pineal gland (arrestin)
  • domestic guinea pig(100307116) retinal S-antigen

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SAG antibody produced in mouse, purified immunoglobulin,
Species Reactivity
human
Application
western blot
Anti-SAG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SAG,
Species
human