RCAN1
regulator of calcineurin 1
ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Human RCAN1 (1827), Mouse Rcan1 (54720), Rat Rcan1 (266766), dog RCAN1 (607887), cow RCAN1 (539640), naked mole-rat Rcan1 (101705243), domestic cat RCAN1 (101085821), domestic guinea pig Rcan1 (100724800), chicken RCAN1 (418510)
- Human(1827) Summary: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(54720) regulator of calcineurin 1
- Rat(266766) regulator of calcineurin 1
- dog(607887) regulator of calcineurin 1
- cow(539640) regulator of calcineurin 1
- naked mole-rat(101705243) regulator of calcineurin 1
- domestic cat(101085821) regulator of calcineurin 1
- domestic guinea pig(100724800) regulator of calcineurin 1
- chicken(418510) regulator of calcineurin 1
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Antibodies
Anti-RCAN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-RCAN1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
canine, human, mouse, rat
western blot
Anti-RCAN1, affinity isolated antibody,
bovine, dog, guinea pig, horse, human, mouse, rat, sheep
western blot
Anti-RCAN1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
bovine, canine, human, mouse, rat
ELISA
western blot
western blot
Anti-DSCR1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
human
immunofluorescence
western blot
western blot