Skip to Content
Merck

PSMB1

proteasome (prosome, macropain) subunit, beta type, 1

Synonyms:
HC5, PMSB1, PSC5
Species:
UniProtKB ID:
Gene ID:
  • Human(5689) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]
  • Mouse(19170) proteasome (prosome, macropain) subunit, beta type 1
  • Rat(94198) proteasome (prosome, macropain) subunit, beta type 1
  • dog(475040) proteasome (prosome, macropain) subunit, beta type, 1
  • cow(514237) proteasome (prosome, macropain) subunit, beta type, 1
  • domestic guinea pig(100734982) proteasome (prosome, macropain) subunit, beta type, 1
  • domestic cat(101101060) proteasome (prosome, macropain) subunit, beta type, 1
  • naked mole-rat(101701261) proteasome (prosome, macropain) subunit, beta type, 1
  • sheep(101116408) proteasome (prosome, macropain) subunit, beta type, 1
  • Zebrafish(445413) proteasome (prosome, macropain) subunit, beta type, 1
  • chicken(421551) proteasome (prosome, macropain) subunit, beta type, 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PSMB1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PSMB1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
20S Proteasome Fraction from rabbit, ≥95% (SDS-PAGE), solution,
Species

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PSMB1,
Species
human
MISSION® esiRNA, targeting mouse Psmb1,
Species
mouse