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Merck

PRKAR1B

protein kinase, cAMP-dependent, regulatory, type I, beta

Synonyms:
PRKAR1
Species:
UniProtKB ID:
Gene ID:
  • Human(5575) Summary: Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.[supplied by OMIM, Jun 2009]
  • Mouse(19085) protein kinase, cAMP dependent regulatory, type I beta
  • Rat(25521) protein kinase, cAMP dependent regulatory, type I, beta
  • Zebrafish(767685) protein kinase, cAMP-dependent, regulatory, type I, beta
  • Horse(100054262) protein kinase, cAMP-dependent, regulatory, type I, beta
  • cow(505370) protein kinase, cAMP-dependent, regulatory, type I, beta
  • dog(480805) protein kinase, cAMP-dependent, regulatory, type I, beta
  • domestic cat(101085259) protein kinase, cAMP-dependent, regulatory, type I, beta
  • chicken(416446) protein kinase, cAMP-dependent, regulatory, type I, beta
  • domestic guinea pig(100713839) protein kinase, cAMP-dependent, regulatory, type I, beta
  • naked mole-rat(101700715) protein kinase, cAMP-dependent, regulatory, type I, beta

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PRKAR1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-PRKAR1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
8-(4-Chlorophenylthio)adenosine 3′,5′-cyclic monophosphate sodium salt, ≥97.0% (HPLC), powder,
Species
human
H-89 dihydrochloride hydrate, ≥98% (HPLC), powder,
Species
human
Etazolate hydrochloride, solid,
Species
human
Propentofylline, solid,
Species
human
3-Isobutyl-1-methylxanthine, ≥99% (HPLC), powder,
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Prkar1b,
Species
mouse
MISSION® esiRNA, targeting human PRKAR1B,
Species
human