OGT

O-linked N-acetylglucosamine (GlcNAc) transferase

Synonyms:

HRNT1, O-GLCNAC

Species:

UniProtKB ID:

Gene ID:

Human(8473) Summary: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Mouse(108155) O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Rat(26295) O-linked N-acetylglucosamine (GlcNAc) transferase
domestic cat(101094162) O-linked N-acetylglucosamine (GlcNAc) transferase
dog(480955) O-linked N-acetylglucosamine (GlcNAc) transferase
chicken(422203) O-linked N-acetylglucosamine (GlcNAc) transferase
sheep(101106996) O-linked N-acetylglucosamine (GlcNAc) transferase
cow(532053) O-linked N-acetylglucosamine (GlcNAc) transferase
Horse(100056148) O-linked N-acetylglucosamine (GlcNAc) transferase
Domestic Rabbit(100354727) O-linked N-acetylglucosamine (GlcNAc) transferase
domestic guinea pig(100728617) O-linked N-acetylglucosamine (GlcNAc) transferase

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Product Number

Description

Species Reactivity

Application

Monoclonal Anti-O-GlcNAc antibody produced in mouse, clone 9H6,

Species Reactivity

human

Application