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Merck

IL3RA

interleukin 3 receptor, alpha (low affinity)

Synonyms:
CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra
Species:
UniProtKB ID:
Gene ID:
  • Human(3563) Summary: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]
  • Mouse(16188) interleukin 3 receptor, alpha chain
  • Rat(246144) interleukin 3 receptor, alpha
  • sheep(101113991) interleukin 3 receptor, alpha (low affinity)
  • dog(609293) interleukin 3 receptor, alpha (low affinity)
  • naked mole-rat(101696721) interleukin 3 receptor, alpha (low affinity)
  • cow(100299249) interleukin 3 receptor, alpha (low affinity)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD123Biotin antibody produced in mouse, clone 6H6,
Species Reactivity
human
Application
flow cytometry
Anti-IL3RA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-CD123 antibody produced in mouse, clone 6H6,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD123-APC antibody produced in mouse, clone 6H6,
Species Reactivity
Application
flow cytometry
Anti-IL3RA (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL3RA,
Species
human
MISSION® esiRNA, targeting mouse Il3ra,
Species
mouse