Skip to Content
Merck

IL2RA

interleukin 2 receptor, alpha

Synonyms:
CD25, IDDM10, IL2R, TCGFR
Species:
Human IL2RA (3559), Mouse Il2ra (16184), Rat Il2ra (25704), dog IL2RA (403870), chicken IL2RA (395294), cow IL2RA (281861), Horse IL2RA (100070292), domestic cat IL2RA (493953), domestic guinea pig Il2ra (100715332), sheep IL2RA (443435)
UniProtKB ID:
P01589, Q5W007
Gene ID:
  • Human(3559) Summary: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
  • Mouse(16184) interleukin 2 receptor, alpha chain
  • Rat(25704) interleukin 2 receptor, alpha
  • dog(403870) interleukin 2 receptor, alpha
  • chicken(395294) interleukin 2 receptor, alpha
  • cow(281861) interleukin 2 receptor, alpha
  • Horse(100070292) interleukin 2 receptor, alpha
  • domestic cat(493953) interleukin 2 receptor, alpha
  • domestic guinea pig(100715332) interleukin 2 receptor, alpha
  • sheep(443435) interleukin 2 receptor, alpha
  • naked mole-rat(101696651) interleukin 2 receptor, alpha

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
RAB0545
Human IL2RA / Interleukin-2 Receptor Subunit Alpha ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
RAB1909
Rat IL-2 R alpha ELISA, for serum, plasma and cell culture supernatants,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
SAB4702052
Monoclonal Anti-CD25 PE-Cyanine7 produced in mouse, ,
Species Reactivity
human
Application
flow cytometry
SAB4700364
Monoclonal Anti-CD25-PE antibody produced in mouse, clone MEM-181, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
SAB5500055
Anti-CD25 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP176, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
SAB4504239
Anti-phospho-IL-2R α/CD25 (pSer268) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
SAB4501537
Anti-IL-2R α antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot

Proteins

Product Number
Description
Species
I0779
Interleukin-2 Soluble Receptor α human, >97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
EHU078131
MISSION® esiRNA, targeting human IL2RA,
Species
human