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Merck

CHRM3

cholinergic receptor, muscarinic 3

Synonyms:
EGBRS, HM3
Species:
Human CHRM3 (1131), Mouse Chrm3 (12671), Rat Chrm3 (24260), Domestic Rabbit CHRM3 (100355313), sheep CHRM3 (443189), domestic cat CHRM3 (101100919), cow CHRM3 (281685), Horse CHRM3 (100056633), dog CHRM3 (403827), domestic guinea pig Chrm3 (100379235)
UniProtKB ID:
P20309, Q0VAJ8, Q4QRI3, Q5VXY2, Q9HB60
Gene ID:
  • Human(1131) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq, Jul 2008]
  • Mouse(12671) cholinergic receptor, muscarinic 3, cardiac
  • Rat(24260) cholinergic receptor, muscarinic 3
  • Domestic Rabbit(100355313) cholinergic receptor, muscarinic 3
  • sheep(443189) cholinergic receptor, muscarinic 3
  • domestic cat(101100919) cholinergic receptor, muscarinic 3
  • cow(281685) cholinergic receptor, muscarinic 3
  • Horse(100056633) cholinergic receptor, muscarinic 3
  • dog(403827) cholinergic receptor, muscarinic 3
  • domestic guinea pig(100379235) cholinergic receptor, muscarinic 3, cardiac
  • chicken(396364) cholinergic receptor, muscarinic 3

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Small Molecule - Agonist

Product Number
Description
Species
PHR1511
Carbachol, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1092009
Carbachol, United States Pharmacopeia (USP) Reference Standard,
Species
human
A6500
Acetylcholine bromide, ≥99%,
Species
human
A2126
Acetyl-β-methylcholine bromide, ≥99%,
Species
human
A7000
Acetylcholine iodide, ≥97%,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Y0001088
Cyclopentolate for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
1347507
Ipratropium bromide, United States Pharmacopeia (USP) Reference Standard,
Species
human
CDS021533
Cyclopentolate, ,
Species
human
I0360000
Ipratropium bromide, European Pharmacopoeia (EP) Reference Standard,
Species
human
C3245000
Cyclopentolate hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
HPA024106
Anti-CHRM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
SAB5700750
Anti-CHRM3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
HPA048036
Anti-CHRM3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
M0194
Anti-Muscarinic Acetylcholine Receptor (M3) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Species
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Species
human
51330
Harmaline, ≥95%,
Species
human, rat

Small Molecule - Ligand

Product Number
Description
Species
A138
Aminobenztropine, solid,
Species
human

esiRNA

Product Number
Description
Species
EHU027151
MISSION® esiRNA, targeting human CHRM3,
Species
human