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Merck

APOE

apolipoprotein E

Synonyms:
AD2, LDLCQ5, LPG
Species:
Human APOE (348), Mouse Apoe (11816), Rat Apoe (25728), naked mole-rat Apoe (101717206), domestic guinea pig Apoe (100731633), cow APOE (281004), Domestic Rabbit APOE (100009337), dog APOE (476438), domestic cat APOE (101086769)
UniProtKB ID:
P02649, B2RC15, C0JYY5, Q9P2S4
Gene ID:
  • Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
  • Mouse(11816) apolipoprotein E
  • Rat(25728) apolipoprotein E
  • naked mole-rat(101717206) apolipoprotein E
  • domestic guinea pig(100731633) apolipoprotein E
  • cow(281004) apolipoprotein E
  • Domestic Rabbit(100009337) apolipoprotein E
  • dog(476438) apolipoprotein E
  • domestic cat(101086769) apolipoprotein E

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ELISA

Product Number
Description
Species
RAB0613
Human APOE / Apolipoprotein E ELISA Kit, ,
Species
human
RAB0616
Human APOE / Apolipoprotein E 4 ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB2500086
Anti-APOE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
ZRB1910
Anti-ApoE Antibody, clone 3N14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunocytochemistry
SAB2109081
Anti-APOE (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat, zebrafish
Application
immunohistochemistry
western blot
SAB2701946
Anti-APOE (C-terminal) antibody produced in rabbit, ,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA065539
Anti-APOE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP4760
ApoE2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
Species
human
SRP6303
Apolipoprotein E from human plasma, ≥95% (SDS-PAGE),
Species
human
A3234
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
Species
human
L7914
Lipoprotein, low density from human plasma, ≥95% (SDS-PAGE), solution,
Species
human
L8039
Lipoprotein, high density from human plasma, ≥95% (SDS-PAGE), solution,
Species
human

esiRNA

Product Number
Description
Species
EMU031371
MISSION® esiRNA, targeting mouse Apoe,
Species
mouse