Skip to Content
Merck
  • A novel approach for electromembrane extraction based on the use of silver nanometallic-decorated hollow fibers.

A novel approach for electromembrane extraction based on the use of silver nanometallic-decorated hollow fibers.

Analytica chimica acta (2014-10-11)
María Ramos-Payán, Rut Fernández-Torres, Juan Luis Pérez-Bernal, Manuel Callejón-Mochón, Miguel Ángel Bello-López
ABSTRACT

A novel approach based on the use of nanometallic-decorated hollow fibers to assist electromembrane extraction is proposed. Microporous polypropylene hollow fibers, on which nanometallic silver was deposited, have been used for the first time as liquid membrane support in electromembrane extraction (EME). Different methods for the generation/deposition of silver nanoparticles (AgNPs) were studied. The best results were obtained with chemical reduction of silver nitrate using NaBH4 in aqueous solution followed by direct deposition on the hollow fibers. The extraction performance of the new supports was compared with a previously developed EME procedure used for the extraction of selected non-steroidal anti-inflammatory drugs (NSAIDs), resulting in an increase in the extraction ratio by a factor of 1.2-2 with a 30% reduction in the extraction time. The new nanometallic-decorated supports open new possibilities for EME due to the singular properties of nanometallic particles, including chemical fiber functionalization.

MATERIALS
Product Number
Brand
Product Description

Supelco
Citric acid, Anhydrous, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Ascorbic Acid, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Naproxen, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Citric acid, ACS reagent, ≥99.5%
USP
Ascorbic acid, United States Pharmacopeia (USP) Reference Standard
Sigma-Aldrich
(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, 98%
Supelco
Naproxen, VETRANAL®, analytical standard
Sigma-Aldrich
Sodium borohydride, granular, 99.99% trace metals basis
Sigma-Aldrich
Sodium borohydride, ReagentPlus®, 99%
Sigma-Aldrich
Sodium borohydride, purum p.a., ≥96% (gas-volumetric)
Sigma-Aldrich
Citric acid, ≥99.5%, FCC, FG
Sigma-Aldrich
Citric acid, BioUltra, anhydrous, ≥99.5% (T)
Sigma-Aldrich
Sodium borohydride, caplets (18 × 10 × 8 mm), 98%
Sigma-Aldrich
Sodium borohydride, powder, ≥98.0%
Sigma-Aldrich
2-Hydroxybutyric acid sodium salt, 97%
Sigma-Aldrich
Sodium borohydride, granular, 10-40 mesh, 98%
Sigma-Aldrich
Ketoprofen, meets USP testing specifications
Sigma-Aldrich
Ketoprofen, ≥98% (TLC)
Sigma-Aldrich
Citric acid, anhydrous, suitable for cell culture, suitable for plant cell culture
Sigma-Aldrich
Citric acid, 99%
Sigma-Aldrich
Naproxen, meets USP testing specifications
Ascorbic acid, European Pharmacopoeia (EP) Reference Standard
Supelco
Ketoprofen, VETRANAL®, analytical standard
Citric acid, anhydrous, European Pharmacopoeia (EP) Reference Standard
USP
Citric acid, United States Pharmacopeia (USP) Reference Standard
USP
Naproxen, United States Pharmacopeia (USP) Reference Standard
Supelco
Citric acid, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Sigma-Aldrich
Citric acid, anhydrous, free-flowing, Redi-Dri, ACS reagent, ≥99.5%
Naproxen, European Pharmacopoeia (EP) Reference Standard
Supelco
Ketoprofen, Pharmaceutical Secondary Standard; Certified Reference Material