- Is the induction of neuroblastoma differentiation by CCA mediated by its effects on the electrochemical gradient?
Is the induction of neuroblastoma differentiation by CCA mediated by its effects on the electrochemical gradient?
FEBS letters (1984-07-23)
J L Vayssière, F Berthelot, F Gros, B Croizat
PMID6745427
ABSTRACT
Various mitochondrial inhibitors are tested in neuroblastoma cells. Their effects on the mit-proteins and some cytoskeletal proteins are compared to those of CCA, a differentiation inducer. This comparison favours the hypothesis that the primary effect of CCA induction is an alteration of the electrochemical gradient.
MATERIALS