- Electrical conduction through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA molecules.
Electrical conduction through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA molecules.
Physical review letters (2001-11-03)
K H Yoo, D H Ha, J O Lee, J W Park, J Kim, J J Kim, H Y Lee, T Kawai, H Y Choi
PMID11690458
ABSTRACT
We report direct measurements of electrical transport through poly(dA)-poly(dT) and poly(dG)-poly(dC) DNA molecules containing identical base pairs. The observed experimental results suggest that electrical transport through DNA molecules occurs by polaron hopping. We have also investigated the effect of gate voltage on the current-voltage curve. It demonstrates the possibility of a DNA field-effect transistor operating at room temperature. Moreover, the gate-voltage dependent transport measurements show that poly(dA)-poly(dT) behaves as an n-type semiconductor, whereas poly(dG)-poly(dC) behaves as a p-type semiconductor.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Polydeoxyadenylic acid • Polythymidylic acid sodium salt, double-stranded homopolymer