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G004632

HPLC Analysis of Metoprolol Enantiomers on Astec® CHIROBIOTIC® V

application for HPLC

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About This Item

technique(s)

HPLC: suitable

test parameters

column: CHIROBIOTIC V, 25 cm x 4.6 mm I.D., 5 μm particles (11024AST)
mobile phase: [A] methanol; [B] acetic acid; [C] triethylamine; (99.8:0.1:0.1, A:B:C)
flow rate: 0.5 mL/min
column temp.: 20 °C
detector: UV, 225 nm
injection: 2 μL
sample: 1 mg/mL in methanol

suitability

application for HPLC

application(s)

pharmaceutical (small molecule)

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

Analyte

Description
    (±)-Metoprolol (+)-tartrate salt, ≥98% (titration), powder

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