STRADB
STE20-related kinase adaptor beta
Synonyms:
ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK
Species:
Human STRADB (55437), Mouse Stradb (227154), Rat Stradb (501146), domestic guinea pig Stradb (100712796), cow STRADB (506029), sheep STRADB (101108549), dog STRADB (478870), Goat STRADB (100861151), Domestic Rabbit STRADB (100342882), naked mole-rat Stradb (101700434) ...More
UniProtKB ID:
Gene ID:
- Human(55437) Summary: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
- Mouse(227154) STE20-related kinase adaptor beta
- Rat(501146) STE20-related kinase adaptor beta
- domestic guinea pig(100712796) STE20-related kinase adaptor beta
- cow(506029) STE20-related kinase adaptor beta
- sheep(101108549) STE20-related kinase adaptor beta
- dog(478870) STE20-related kinase adaptor beta
- Goat(100861151) STE20-related kinase adaptor beta
- Domestic Rabbit(100342882) STE20-related kinase adaptor beta
- naked mole-rat(101700434) STE20-related kinase adaptor beta
- domestic cat(101094615) STE20-related kinase adaptor beta
- Horse(100066574) STE20-related kinase adaptor beta
- chicken(424083) STE20-related kinase adaptor beta
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ILPIP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
ANTI-MOUSE STRADB (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot
Anti-STRADB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-STRADB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot