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Merck

SRF

serum response factor (c-fos serum response element-binding transcription factor)

Synonyms:
MCM1
Species:
UniProtKB ID:
Gene ID:
  • Human(6722) Summary: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008]
  • Mouse(20807) serum response factor
  • Rat(501099) serum response factor (c-fos serum response element-binding transcription factor)
  • fruit fly(252723) Surf wings
  • chicken(396103) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic cat(101085210) serum response factor (c-fos serum response element-binding transcription factor)
  • dog(612861) serum response factor (c-fos serum response element-binding transcription factor)
  • cow(533039) serum response factor (c-fos serum response element-binding transcription factor)
  • sheep(101111402) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic guinea pig(100715998) serum response factor (c-fos serum response element-binding transcription factor)
  • naked mole-rat(101719000) serum response factor (c-fos serum response element-binding transcription factor)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SRF antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse
Application
ELISA
western blot
Anti-SRF Antibody, clone 1H14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-SRF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-SRF antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-phospho-SRF (pSer99) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
C-fos, proto oncogene human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SRF,
Species
human