SPDEF
SAM pointed domain containing ETS transcription factor
Synonyms:
PDEF, RP11-375E1__A.3, bA375E1.3
Species:
Human SPDEF (25803), Mouse Spdef (30051), Rat Spdef (689210), naked mole-rat Spdef (101698462), sheep SPDEF (101120201), chicken SPDEF (428271), domestic guinea pig Spdef (100726493), dog SPDEF (481751), cow SPDEF (497620), domestic cat SPDEF (101096315)
UniProtKB ID:
Gene ID:
- Human(25803) Summary: The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
- Mouse(30051) SAM pointed domain containing ets transcription factor
- Rat(689210) SAM pointed domain containing ets transcription factor
- naked mole-rat(101698462) SAM pointed domain containing ets transcription factor
- sheep(101120201) SAM pointed domain containing ets transcription factor
- chicken(428271) SAM pointed domain containing ets transcription factor
- domestic guinea pig(100726493) SAM pointed domain containing ets transcription factor
- dog(481751) SAM pointed domain containing ets transcription factor
- cow(497620) SAM pointed domain containing ets transcription factor
- domestic cat(101096315) SAM pointed domain containing ets transcription factor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SPDEF (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, rabbit
Application
western blot
Anti-SPDEF (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SPDEF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-SPDEF (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-SPDEF antibody produced in mouse, clone 4A5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot