RNF20
ring finger protein 20, E3 ubiquitin protein ligase
Synonyms:
BRE1, BRE1A, hBRE1
Species:
Human RNF20 (56254), Mouse Rnf20 (109331), Rat Rnf20 (313216), Zebrafish rnf20 (402838), domestic cat RNF20 (101097522), cow RNF20 (513326), dog RNF20 (474788), chicken RNF20 (427310), naked mole-rat Rnf20 (101711656), domestic guinea pig Rnf20 (100717191) ...More
UniProtKB ID:
Gene ID:
- Human(56254) Summary: The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
- Mouse(109331) ring finger protein 20
- Rat(313216) ring finger protein 20, E3 ubiquitin protein ligase
- Zebrafish(402838) ring finger protein 20, E3 ubiquitin protein ligase
- domestic cat(101097522) ring finger protein 20, E3 ubiquitin protein ligase
- cow(513326) ring finger protein 20
- dog(474788) ring finger protein 20, E3 ubiquitin protein ligase
- chicken(427310) ring finger protein 20, E3 ubiquitin protein ligase
- naked mole-rat(101711656) ring finger protein 20, E3 ubiquitin protein ligase
- domestic guinea pig(100717191) ring finger protein 20, E3 ubiquitin protein ligase
- Domestic Rabbit(100340973) ring finger protein 20, E3 ubiquitin protein ligase
- Horse(100054384) ring finger protein 20, E3 ubiquitin protein ligase
- sheep(101121065) ring finger protein 20, E3 ubiquitin protein ligase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Rnf20 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-hRNF20 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-RNF20 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-RNF20 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-RNF20 antibody produced in mouse, clone 1C6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
RNF20 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species