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Merck

PFKM

phosphofructokinase, muscle

Synonyms:
GSD7, PFK-1, PFK1, PFKA, PFKX
Species:
UniProtKB ID:
Gene ID:
  • Human(5213) Summary: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
  • Mouse(18642) phosphofructokinase, muscle
  • Rat(65152) phosphofructokinase, muscle
  • domestic cat(101088852) phosphofructokinase, muscle
  • Horse(100034116) phosphofructokinase, muscle
  • Domestic Rabbit(100345647) phosphofructokinase, muscle
  • chicken(374064) phosphofructokinase, muscle
  • domestic guinea pig(100733625) phosphofructokinase, muscle
  • cow(506544) phosphofructokinase, muscle
  • naked mole-rat(101705614) phosphofructokinase, muscle
  • dog(403849) phosphofructokinase, muscle

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PFKM Antibody, clone 4Z7X1, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-PFKM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PFKM antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-PFKM antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
western blot

Kits

Product Number
Description
Species
Phosphofructokinase (PFK) Activity Colorimetric Assay Kit, sufficient for 100 colorimetric tests,
Species
mouse, rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Pfkm,
Species
mouse
MISSION® esiRNA, targeting human PFKM,
Species
human