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Merck

KCNA6

potassium voltage-gated channel, shaker-related subfamily, member 6

Synonyms:
HBK2, KV1.6
Species:
Human KCNA6 (3742), Mouse Kcna6 (16494), Rat Kcna6 (64358), cow KCNA6 (539714), domestic cat KCNA6 (101093113), Horse KCNA6 (100051577), dog KCNA6 (486733), Zebrafish kcna6 (795490), domestic guinea pig Kcna6 (100718638), Domestic Rabbit KCNA6 (100353348)
UniProtKB ID:
P17658
Gene ID:
  • Human(3742) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12. [provided by RefSeq, Jul 2008]
  • Mouse(16494) potassium voltage-gated channel, shaker-related, subfamily, member 6
  • Rat(64358) potassium voltage gated channel, shaker related subfamily, member 6
  • cow(539714) potassium voltage-gated channel, shaker-related subfamily, member 6
  • domestic cat(101093113) potassium voltage-gated channel, shaker-related subfamily, member 6
  • Horse(100051577) potassium voltage-gated channel, shaker-related subfamily, member 6
  • dog(486733) potassium voltage-gated channel, shaker-related subfamily, member 6
  • Zebrafish(795490) potassium voltage-gated channel, shaker-related, subfamily, member 6
  • domestic guinea pig(100718638) potassium voltage-gated channel, shaker-related subfamily, member 6
  • Domestic Rabbit(100353348) potassium voltage-gated channel, shaker-related subfamily, member 6

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA076475
Anti-Kcna6 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
SAB5200061
Monoclonal Anti-KCNA6 antibody produced in mouse, clone S19-36, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

Small Molecule - Blocker

Product Number
Description
Species
50937
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
Species
human
G9284
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Species
human
1162454
Dalfampridine, United States Pharmacopeia (USP) Reference Standard,
Species
human
50940
Guanidine hydrochloride, ≥99.0% (AT),
Species
human
G11659
Guanidine carbonate salt, 99%,
Species
human

esiRNA

Product Number
Description
Species
EHU144431
MISSION® esiRNA, targeting human KCNA6, GALNT8,
Species
human
EMU083511
MISSION® esiRNA, targeting mouse Kcna6,
Species
mouse