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Merck

KAT2B

K(lysine) acetyltransferase 2B

Synonyms:
CAF, P, P/CAF, PCAF
Species:
UniProtKB ID:
Gene ID:
  • Human(8850) Summary: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]
  • Mouse(18519) K(lysine) acetyltransferase 2B
  • sheep(101115756) K(lysine) acetyltransferase 2B
  • dog(477052) K(lysine) acetyltransferase 2B
  • naked mole-rat(101711015) K(lysine) acetyltransferase 2B
  • domestic guinea pig(100719014) K(lysine) acetyltransferase 2B
  • Horse(100061976) K(lysine) acetyltransferase 2B
  • chicken(428441) K(lysine) acetyltransferase 2B
  • domestic cat(101080732) K(lysine) acetyltransferase 2B
  • Zebrafish(563942) K(lysine) acetyltransferase 2B
  • cow(407215) K(lysine) acetyltransferase 2B

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PCAF antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
immunoprecipitation (IP)
microarray

western blot
Anti-KAT2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-p300 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-PCAF antibody produced in mouse, clone 1H2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-p300/CBP antibody, Mouse monoclonal, clone NM11, purified from hybridoma cell culture,
Species Reactivity
human, mink, monkey, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)

microarray

western blot

Small Molecule - Cofactor

Product Number
Description
Species
Acetyl coenzyme A lithium salt, ≥93% (HPLC),
Species
human, mouse, rat
Acetyl coenzyme A trisodium salt, ≥93% (HPLC), powder,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Kat2b,
Species
mouse
MISSION® esiRNA, targeting human KAT2B,
Species
human