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Merck

ILF3

interleukin enhancer binding factor 3, 90kDa

Synonyms:
CBTF, DRBF, DRBP76, MMP4, MPHOSPH4, MPP4, NF-AT-90, NF110, NF110b, NF90, NF90a, NF90b, NFAR, NFAR-1, NFAR2, TCP110, TCP80
Species:
UniProtKB ID:
Gene ID:
  • Human(3609) Summary: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT); a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
  • Mouse(16201) interleukin enhancer binding factor 3
  • Rat(84472) interleukin enhancer binding factor 3
  • dog(484950) interleukin enhancer binding factor 3, 90kDa
  • sheep(101118785) interleukin enhancer binding factor 3, 90kDa
  • domestic guinea pig(100717410) interleukin enhancer binding factor 3, 90kDa
  • Horse(100057707) interleukin enhancer binding factor 3, 90kDa
  • domestic cat(101096038) interleukin enhancer binding factor 3, 90kDa
  • naked mole-rat(101723927) interleukin enhancer binding factor 3, 90kDa
  • cow(614936) interleukin enhancer binding factor 3, 90kDa

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ILF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ILF3 Antibody, clone 0S2N7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-DRBP76/ILF3 Antibody, serum, from rabbit,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ILF3,
Species
human
MISSION® esiRNA, targeting mouse Ilf3,
Species
mouse