CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
Synonyms:
CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Species:
Human CCR5 (1234), Mouse Ccr5 (12774), Rat Ccr5 (117029), domestic guinea pig Ccr5 (100716672), naked mole-rat Ccr5 (101723738), Horse CCR5 (100048935), cow CCR5 (497017), sheep CCR5 (101117453), domestic cat CCR5 (493769), chicken CCR5 (420695) ...More
UniProtKB ID:
Gene ID:
- Human(1234) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12774) chemokine (C-C motif) receptor 5
- Rat(117029) chemokine (C-C motif) receptor 5
- domestic guinea pig(100716672) chemokine (C-C motif) receptor 5
- naked mole-rat(101723738) chemokine (C-C motif) receptor 5
- Horse(100048935) chemokine (C-C motif) receptor 5
- cow(497017) chemokine (C-C motif) receptor 5
- sheep(101117453) chemokine (C-C motif) receptor 5
- domestic cat(493769) chemokine (C-C motif) receptor 5
- chicken(420695) chemokine (C-C motif) receptor 5
- dog(484789) chemokine (C-C motif) receptor 5
- Domestic Rabbit(100101579) chemokine (C-C motif) receptor 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CCR5 (CD195) Antibody, clone HEK/1/85a/7a, clone HEK/1/85a/7a, from rat,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunocytochemistry
Anti-CCR5 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CCR5, C-Terminal antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-C-C Chemokine Receptor 5 Antibody, NT, Chemicon®, from rabbit,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CD195-APC antibody produced in mouse, clone T21/8,
Species Reactivity
Application
flow cytometry