Skip to Content
Merck

CASP7

caspase 7, apoptosis-related cysteine peptidase

Synonyms:
CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Species:
UniProtKB ID:
Gene ID:
  • Human(840) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(12369) caspase 7
  • Rat(64026) caspase 7
  • Goat(100861343) caspase 7, apoptosis-related cysteine peptidase
  • dog(486896) caspase 7, apoptosis-related cysteine peptidase
  • Zebrafish(553634) caspase 7, apoptosis-related cysteine peptidase
  • chicken(423901) caspase 7, apoptosis-related cysteine peptidase
  • naked mole-rat(101709568) caspase 7, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715159) caspase 7, apoptosis-related cysteine peptidase
  • cow(526279) caspase 7, apoptosis-related cysteine peptidase
  • sheep(101122741) caspase 7, apoptosis-related cysteine peptidase
  • domestic cat(768262) caspase 7, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human Caspase-7 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CASP7 (Cleaved-Asp198) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry

western blot
Anti-Caspase-7 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-CASP7 (p20, Cleaved-Asp198) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
Monoclonal Anti-Caspase 7 antibody produced in rat, clone 11E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunoprecipitation (IP)
microarray

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
N-Acetyl-Asp-Glu-Val-Asp-al, ≥95%, powder,
Species
human
NSCI, ≥97% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CASP7,
Species
human