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Merck

AP2A1

adaptor-related protein complex 2, alpha 1 subunit

Synonyms:
ADTAA, AP2-ALPHA, CLAPA1
Species:
UniProtKB ID:
Gene ID:
  • Human(160) Summary: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(11771) adaptor-related protein complex 2, alpha 1 subunit
  • Rat(308578) adaptor-related protein complex 2, alpha 1 subunit
  • dog(484375) adaptor-related protein complex 2, alpha 1 subunit
  • domestic cat(101101430) adaptor-related protein complex 2, alpha 1 subunit
  • Zebrafish(558153) adaptor-related protein complex 2, alpha 1 subunit
  • Domestic Rabbit(100344131) adaptor-related protein complex 2, alpha 1 subunit
  • Horse(100056103) adaptor-related protein complex 2, alpha 1 subunit
  • cow(784636) adaptor-related protein complex 2, alpha 1 subunit
  • domestic guinea pig(100723156) adaptor-related protein complex 2, alpha 1 subunit
  • sheep(101108595) adaptor-related protein complex 2, alpha 1 subunit
  • naked mole-rat(101715441) adaptor-related protein complex 2, alpha 1 subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-AP2A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
horse, human
Application
western blot
Anti-AP2A1, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Monoclonal Anti-α-Adaptin antibody produced in mouse, clone 100/2, ascites fluid,
Species Reactivity
bovine, human, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AP2A1,
Species
human
MISSION® esiRNA, targeting mouse Ap2a1,
Species
mouse