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Merck

ALDOA

aldolase A, fructose-bisphosphate

Synonyms:
ALDA, GSD12
Species:
UniProtKB ID:
Gene ID:
  • Human(226) Summary: The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]
  • Mouse(11674) aldolase A, fructose-bisphosphate
  • Rat(24189) aldolase A, fructose-bisphosphate
  • domestic cat(101100776) aldolase A, fructose-bisphosphate
  • chicken(396078) aldolase A, fructose-bisphosphate
  • sheep(443085) aldolase A, fructose-bisphosphate
  • naked mole-rat(101702582) aldolase A, fructose-bisphosphate
  • Domestic Rabbit(100009055) aldolase A, fructose-bisphosphate
  • Horse(100066121) aldolase A, fructose-bisphosphate
  • dog(479787) aldolase A, fructose-bisphosphate
  • cow(509566) aldolase A, fructose-bisphosphate
  • domestic guinea pig(100730400) aldolase A, fructose-bisphosphate

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ALDOA antibody produced in mouse, clone 3D9-6F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Monoclonal Anti-ALDOA antibody produced in mouse, clone 2E6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
ANTI-ALDOLASE (ALDOA)(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ALDOA antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, human, rabbit
Application
western blot
Anti-ALDOA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Kits

Product Number
Description
Species
Aldolase Activity Colorimetric Assay Kit, Sufficient for 100 Colorimetric tests,
Species
mouse, human, rat

Proteins

Product Number
Description
Species
Aldolase A human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Aldoa,
Species
mouse
MISSION® esiRNA, targeting human ALDOA,
Species
human