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Merck

ALDH6A1

aldehyde dehydrogenase 6 family, member A1

Synonyms:
MMSADHA, MMSDH
Species:
UniProtKB ID:
Gene ID:
  • Human(4329) Summary: This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
  • Mouse(104776) aldehyde dehydrogenase family 6, subfamily A1
  • Rat(81708) aldehyde dehydrogenase 6 family, member A1
  • naked mole-rat(101705709) aldehyde dehydrogenase 6 family, member A1
  • domestic guinea pig(100732213) aldehyde dehydrogenase 6 family, member A1
  • dog(490779) aldehyde dehydrogenase 6 family, member A1
  • sheep(101106176) aldehyde dehydrogenase 6 family, member A1
  • cow(327692) aldehyde dehydrogenase 6 family, member A1
  • domestic cat(101090776) aldehyde dehydrogenase 6 family, member A1
  • Zebrafish(436647) aldehyde dehydrogenase 6 family, member A1
  • chicken(423345) aldehyde dehydrogenase 6 family, member A1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ALDH6A1 (C-term) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-ALDH6A1 (N-term) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-ALDH6A1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ALDH6A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab4,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-ALDH6A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab3,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Aldh6a1,
Species
mouse
MISSION® esiRNA, targeting human ALDH6A1,
Species
human