243973

Sodium bisulfite

ACS reagent

• Synonym(s): Sodium hydrogensulfite
• Empirical Formula (Hill Notation): NaHSO₃
• CAS Number: 7631-90-5
• Molecular Weight: 104.06
• UNSPSC Code: 12352302
• PubChem Substance ID: 24854644
• NACRES: NA.21

Properties

• grade: ACS reagent
• Quality Level: 200
• form: powder or crystals
• concentration: ≥58.5% SO₂
• impurities: ≤0.005% insolubles
• pH: 4.3 (10 g/L)
• anion traces: chloride (Cl^-): ≤0.02%
• cation traces: Fe: ≤0.002%; heavy metals (as Pb): ≤0.001%
• SMILES string: [Na+].OS([O-])=O
• InChI: 1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-2
• InChI key: DWAQJAXMDSEUJJ-UHFFFAOYSA-L

Description

General description

Sodium bisulfite is a widely used industrial chemical as a reducing agent, catalyst, and preservative in pharmaceuticals and foods due to its antioxidative and antibacterial effects.

The aqueous solutions of sodium bisulfite are acidic in nature. Degradation of sodium bisulfite with acid forms sulfur dioxide gas.

Application

Sodium bisulfite (NaHSO₃) has been used as a reagent to compose the immunoprecipitation (IP) buffer to chemically modify DNA and to synthesize arsenolipids (AsL).
It can also be used as a reagent during the synthesis of 5,6-dihydrouracil-6-sulfonate.

Sodium bisulfite can be used as:

• A reagent to synthesize aldehyde-bisulfite adducts from aromatic and aliphatic aldehydes.
• A catalyst in the solvent-free etherification of aromatic/aliphatic alcohols to synthesize symmetric and unsymmetric ethers via intermolecular dehydration.
• An additive in the copper-catalyzed homocoupling of ketoxime carboxylates to synthesize symmetrical pyrroles.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Supplementary Hazards: EUH031
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable