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Cimaterol

VETRANAL®, analytical standard

Synonym(s):

2-Amino-5-(1-hydroxy-2-isopropylaminoethyl)benzonitrile

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About This Item

Empirical Formula (Hill Notation):
C12H17N3O
CAS Number:
Molecular Weight:
219.28
Beilstein:
2418129
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

CC(C)NCC(O)c1ccc(N)c(c1)C#N

InChI

1S/C12H17N3O/c1-8(2)15-7-12(16)9-3-4-11(14)10(5-9)6-13/h3-5,8,12,15-16H,7,14H2,1-2H3

InChI key

BUXRLJCGHZZYNE-UHFFFAOYSA-N

General description

Cimaterol is a β-adrenergic agonist.
Cimaterol is classified under the β-agonist class of drugs.

Application

Cimaterol may be used as a reference standard for the determination of the analyte in animal tissues, feeding-stuffs, and feces by high-performance liquid chromatography and post-column derivatization.
Cimaterol may be used as an analytical reference standard for the determination of the analyte in:
  • Feed samples by solid-phase extraction (SPE) and ultra-performance liquid chromatography (UPLC).
  • Pig liver, kidney and muscle samples by SPE and UPLC coupled to tandem mass spectrometry (MS/MS).
  • Bovine retina by SPE and gas chromatography-mass spectrometry (GC-MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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High-performance liquid chromatographic determination of clenbuterol and cimaterol using post-column derivatization.
Courtheyn D, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 564(2), 537-549 (1991)
F H Chikhou et al.
Journal of animal science, 71(4), 906-913 (1993-04-01)
The objectives of this experiment were: 1) to determine whether feeding cimaterol to male calves from 4 wk of age until slaughter at target live weights of 275, 375, or 475 kg would result in a sustained increase in growth
T M Byrem et al.
Journal of animal science, 76(4), 988-998 (1998-05-15)
Our objective was to determine whether the chronic anabolic effects of beta-adrenergic agonists on skeletal muscle are direct and how long they are maintained. We studied acute (6 h) and chronic (1 to 20 d) effects of cimaterol (CIM) on
Gas chromatography-mass spectrometry analysis of β2-agonists in bovine retina.
Hernandez-Carrasquilla M
Analytica Chimica Acta, 408(1-2), 285-290 (2000)
B L Gwartney et al.
Journal of animal science, 70(7), 2144-2150 (1992-07-01)
The response time to cimaterol (CIM), a beta-adrenergic agonist, by broiler chickens for carcass characteristics, muscle composition, muscle fiber size, catheptic enzyme activity, and tenderness was determined. Two trials were conducted in which chickens were fed a control diet (CON)

Articles

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

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