If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
V3501
Vitamin K1
viscous liquid
Synonym(s):
2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K1(20)
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| Size/SKU | Availability | Price |
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About This Item
biological source
synthetic (organic
inorganic)
Quality Segment
form
viscous liquid
color
, Yellow to Very Dark Yellow to Very Dark Orange
refractive index
n20/D 1.527 (lit.)
mp
−20 °C (lit.)
density
0.984 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O
InChI
1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
InChI key
MBWXNTAXLNYFJB-NKFFZRIASA-N
General description
Application
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| biological source synthetic (organic | biological source - | biological source - | biological source synthetic |
| form viscous liquid | form liquid | form liquid | form viscous liquid |
| storage temp. 2-8°C | storage temp. −70°C | storage temp. 15-25°C | storage temp. 2-8°C |
| Quality Level 100 | Quality Level 300 | Quality Level 500 | Quality Level 200 |
| color , Yellow to Very Dark Yellow to Very Dark Orange | color - | color - | color light green-yellow to dark green-yellow, light yellow to dark yellow |
| mp −20 °C (lit.) | mp -143.99 °C | mp -20 °C | mp −20 °C (lit.) |
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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How can I determine the shelf life / expiration / retest date of this product?
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Helpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
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How much of Vitamin K1 per litre of anaerobic gut-mimicking media is recommended?
1 answer-
This is not an application that is QC tested, but the literature indicates that a good starting point might be 0.5 ug/mL. Please see: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658209/
Another option would be to use a Vitamin K1 ready-made solution, such as: https://www.sigmaaldrich.com/product/sigma/sbr00053
This product is at a concentration of 5 mg/mL, but recommends dilution down to 1 ug/mL prior to use, and states that the optimal concentration may vary by strain so, further experimentation may be necessary to determine optimal conditions.
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