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Key Documents

D2631

Sigma-Aldrich

Dihexadecyl phosphate

Synonym(s):

DHP, Dicetyl phosphate

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About This Item

Linear Formula:
[CH3(CH2)15O]2P(O)OH
CAS Number:
Molecular Weight:
546.85
Beilstein:
1717117
EC Number:
MDL number:
UNSPSC Code:
51191904
PubChem Substance ID:
NACRES:
NA.25

description

anionic

form

powder

mol wt

546.85 g/mol

technique(s)

DNA extraction: suitable

mp

74-75 °C (lit.)

lipid type

phospholipids

storage temp.

−20°C

SMILES string

OP(OCCCCCCCCCCCCCCCC)(OCCCCCCCCCCCCCCCC)=O

InChI

1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)

InChI key

RNPXCFINMKSQPQ-UHFFFAOYSA-N

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Biochem/physiol Actions

Dihexadecyl phosphate (DHP) is a negatively charged lipid that is used for the formation of model membranes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kenji Suda et al.
Journal of controlled release : official journal of the Controlled Release Society, 266, 301-309 (2017-10-11)
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Ba Hieu Tran et al.
International journal of nanomedicine, 14, 10061-10077 (2020-01-11)
S-propargyl-cysteine (SPRC; alternatively known as ZYZ-802) is a novel modulator of endogenous tissue H2S concentrations with known cardioprotective and anti-inflammatory effects. However, its rapid metabolism and excretion have limited its clinical application. To overcome these issues, we have developed some
Hamdy Abdelkader et al.
Journal of pharmaceutical sciences, 100(5), 1833-1846 (2011-01-20)
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as
Haruyuki Ishii et al.
Colloids and surfaces. B, Biointerfaces, 92, 372-376 (2011-12-16)
Hollow silica particle was obtained with a vesicle template synthesis in water under ambient conditions in the presence of ammonia. Biomimetic vesicles, liposomes were used, which consisted of a zwitterionic phospholipid, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and a tiny amount of charged amphiphiles
Abbas Pardakhty et al.
International journal of pharmaceutics, 328(2), 130-141 (2006-09-26)
In this study, niosomes of polyoxyethylene alkyl ethers (Brij) were prepared for encapsulation of insulin by film hydration method. Without cholesterol, brij 35 and brij 58 did not form niosomes, apparently because of relatively large polar head groups in comparison

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