31737

Sulfamethoxazole

VETRANAL^®, analytical standard

• Synonym(s): 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, N¹-(5-Methylisoxazol-3-yl)sulfanilamide
• Empirical Formula (Hill Notation): C₁₀H₁₁N₃O₃S
• CAS Number: 723-46-6
• Molecular Weight: 253.28
• Beilstein: 6732984
• EC Number: 211-963-3
• MDL number: MFCD00010546
• UNSPSC Code: 41116107
• PubChem Substance ID: 329753910
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
• InChI: 1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
• InChI key: JLKIGFTWXXRPMT-UHFFFAOYSA-N

Description

General description

Sulfamethoxazole is a bacteriostatic antibiotic used in treating coccidiosis, diarrhea and gastroenteritis in humans and is also a known veterinary drug. Sulfamethoxazole in combination with trimethoprim is effective in treating pneumonia. Sulfamethoxazole acts by blocking the folic acid metabolism to produce synergistic antibacterial activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfamethoxazole may be used as a reference standard for the determination of the analyte in:

• Bovine milk by high-performance liquid chromatography method.
• Pharmaceutical formulations and biological samples by capillary electrophoresis (CE) with end-column electrochemical detection (EC).

Recommended products

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS08,GHS09
• Signal Word: Warning
• Hazard Statements: H361fd,H411
• Precautionary Statements: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Hazard Classifications: Aquatic Chronic 2 - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves