901594

Diisopropylcarbodiimide solution

1 M in THF

• Synonym(s): Diisopropylmethanediimine
• Linear Formula: C₇H₁₄N₂
• CAS Number: 693-13-0
• MDL number: MFCD00065689
• UNSPSC Code: 12352111
• NACRES: NA.22

Properties

• form: liquid
• reaction suitability: reaction type: Coupling Reactions
• concentration: 1 M in THF
• density: 0.870 g/mL
• application(s): peptide synthesis
• InChI: 1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3
• InChI key: BDNKZNFMNDZQMI-UHFFFAOYSA-N

Description

Application

Coupling reagent for peptide syntheses.

DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.

Valuable reagent offered as a solution in tetrahydrofuran for more convenient handling.

Safety Information

• Pictograms: GHS02,GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H225,H302,H317,H318,H330,H334,H335,H336,H351
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 2.0 °F
• Flash Point(C): -16.66 °C