B3563

Bifonazole

≥98% (HPLC)

• Synonym(s): 1-(p,α-Diphenylbenzyl)imidazole
• Empirical Formula (Hill Notation): C₂₂H₁₈N₂
• CAS Number: 60628-96-8
• Molecular Weight: 310.39
• EC Number: 262-336-6
• MDL number: MFCD00865567
• UNSPSC Code: 12352200
• PubChem Substance ID: 329773219
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• originator: Bayer
• storage temp.: room temp
• SMILES string: c1ccc(cc1)C(c2ccc(cc2)-c3ccccc3)n4ccnc4
• InChI: 1S/C22H18N2/c1-3-7-18(8-4-1)19-11-13-21(14-12-19)22(24-16-15-23-17-24)20-9-5-2-6-10-20/h1-17,22H
• InChI key: OCAPBUJLXMYKEJ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Bifonazole is an imidazole-based anti-fungal agent with broad spectrum activity against many fungi, molds, yeast and some Gram-positive bacteria. Bifonazole inhibits ergosterol biosynthetic protein 28 and Cytochrome P450 2B4.

Bifonazole is used to treat several infections such as onychomycoses, otomycoses, erythrasma, psoriasis, sebopsoriasis, seborrhoeic dermatitis and rosacea. Bifonazole is also used as an important drug to treat melanoma.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable