M6036
Myoglobin from human heart
≥95% (SDS-PAGE), buffered aqueous glycerol solution
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Recommended Products
General description
Myoglobin is a heme-related, low-molecular-weight protein. It is mainly found in cardiac and skeletal muscle.
Application
Myoglobin from human heart has been used as a negative control in monitoring isoAsp formation during storage. It has also been used as an antigen in the study to identify self-antigens recognized by serum autoantibodies from unimmunized mice strains.
Myoglobin from human heart was used to study the interactions of a platinum (II) 9-aminoacridine complex with proteins and oligonucleotides by ESI-TOF MS. It was also used in the evaluation of plasma myoglobin using the Stratus CS fluorometer.
Biochem/physiol Actions
Myoglobin may help to increase diffusion and also stores O2 in oxidative muscle. It can momentarily act as an oxygen reservoir to supply oxygen when there is inadequate blood oxygen delivery at the time of intense muscular activity.
Physical form
Solution in 20 mM Tris-HCl, 1 mM EDTA and 50% glycerol, pH 8.5, 2 mg protein per mL (Lowry)
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Iron metabolism and its disorders
Clinical biochemistry of domestic animals, 259-285 (2008)
A High-Throughput Bioluminescent Assay to Monitor the Deamidation of Asparagine and Isomerization of Aspartate Residues in Therapeutic Proteins and Antibodies
Hsiao K, et al.
Journal of Pharmaceutical Sciences, 106(6), 1528-1537 (2017)
Signe Helbo et al.
PloS one, 9(5), e97012-e97012 (2014-06-01)
The discovery that cysteine (Cys) S-nitrosation of trout myoglobin (Mb) increases heme O2 affinity has revealed a novel allosteric effect that may promote hypoxia-induced nitric oxide (NO) delivery in the trout heart and improve myocardial efficiency. To better understand this
P Couck et al.
Acta clinica Belgica, 60(2), 75-78 (2005-08-09)
Circulating myoglobin is recognized as an early and sensitive marker of acute coronary diseases. Long turnaround time of myoglobin assays jeopardize their clinical utility. We evaluated the analytical performance of the Stratus CS fluorometric enzyme immunoassay based on dendrimer technology
Autoantibody patterns in diabetes-prone NOD mice and in standard C57BL/6 mice
Quintana F J and Cohen I R
Journal of Autoimmunity, 17(3), 191-197 (2001)
Chromatograms
application for HPLCOur team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service