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Key Documents

G11608

Sigma-Aldrich

Guanidineacetic acid

99%

Synonym(s):

N-Amidinoglycine, N-Guanylglycine, Glycocyamine

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About This Item

Linear Formula:
H2NC(=NH)NHCH2CO2H
CAS Number:
Molecular Weight:
117.11
Beilstein:
1759179
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

99%

mp

300 °C (lit.)

SMILES string

NC(=N)NCC(O)=O

InChI

1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)

InChI key

BPMFZUMJYQTVII-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Stöckler et al.
Pediatric research, 36(3), 409-413 (1994-09-01)
In a patient with extrapyramidal movement disorder and extremely low creatinine concentrations in serum and urine, in vivo proton magnetic resonance spectroscopy disclosed a generalized depletion of creatinine in the brain. Oral substitution of arginine, a substrate for creatine synthesis
David Cheillan et al.
Orphanet journal of rare diseases, 7, 96-96 (2012-12-14)
A population of patients with unexplained neurological symptoms from six major French university hospitals was screened over a 28-month period for primary creatine disorder (PCD). Urine guanidinoacetate (GAA) and creatine:creatinine ratios were measured in a cohort of 6,353 subjects to
Joseph D T Ndika et al.
Molecular genetics and metabolism, 106(1), 48-54 (2012-03-06)
Arginine:glycineamidinotransferase (AGAT/GATM) deficiency has been described in 9 patients across 4 families. Here we describe the clinical outcome and response to creatine supplementation in a patient of the second family affected with AGAT deficiency-a 9-year-old girl. Delayed motor milestones were
Stefan Pilz et al.
Heart (British Cardiac Society), 97(15), 1222-1227 (2011-05-12)
Homoarginine is an amino acid which may play a role in nitric oxide and energy metabolism. Low homoarginine concentrations have previously been linked to increased mortality, but the underlying mechanisms remain unknown. To investigate whether serum homoarginine concentrations are associated
J Michiels et al.
Poultry science, 91(2), 402-412 (2012-01-19)
Creatine, (CREA) a central constituent in energy metabolism, is obtained from dietary animal protein or de novo synthesis from guanidinoacetic acid (GAA). Especially in all-vegetable diets, supplemental CREA or GAA may restore the CREA availability in tissues, and hence, improve

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