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Lasalocid A sodium salt

analytical standard

Synonym(s):

Lasalocid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C34H53NaO8
CAS Number:
Molecular Weight:
612.77
Beilstein:
3875309
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Assay

≥95.0% (HPLC)

form

powder

optical activity

[α]/D -28±3°, c = 1 in methanol

shelf life

limited shelf life, expiry date on the label

mp

175-185 °C
180 °C (dec.) (lit.)

application(s)

clinical testing

storage temp.

2-8°C

SMILES string

[Na+].CC[C@H]([C@H]1O[C@@](CC)(C[C@@H]1C)[C@H]2CC[C@](O)(CC)[C@H](C)O2)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C([O-])=O

InChI

1S/C34H54O8.Na/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39;/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39);/q;+1/p-1

InChI key

RDHDUYAKDYQPEW-UHFFFAOYSA-M

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General description

Lasalocid is an antibacterial agent, belonging to the carboxylic polyether group of antibiotics, produced by the fermentation of Streptomyces lasaliensis. It is commercially available as a sodium salt and is reported to be used as a coccidiostat in poultry.

Application

Lasalocid A sodium salt may be used as an analytical standard for the quantification of lasalocid in the following:
  • Poultry feeds using liquid chromatography with ultraviolet detection (LC-UV).
  • Animal liver and eggs using liquid chromatography coupled to tandem mass spectrometry (LC-MS-MS).
  • Eggs using liquid chromatography-electrospray mass spectrometry (LC-EMS).

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Chiral Drugs: Chemistry and Biological Action (2017)
Determination of lasalocid in eggs using liquid chromatography?electrospray mass spectrometry
Blanchflower JW and Kennedy GD
Analyst, 120(4), 1129-1132 (1995)
Liquid chromatography with ultraviolet detection of lasalocid, monensin, salinomycin and narasin in poultry feeds using pre-column derivatization
Dusi G and Gamba V
Journal of Chromatography A, 835(1-2), 243-246 (1999)
The determination of 5 anticoccidial drugs (nicarbazin, lasalocid, monensin, salinomycin and narasin) in animal livers and eggs by liquid chromatography linked with tandem mass spectrometry (LC-MS-MS)
Matabudul KD, et al.
Analyst, 127(6), 760-768 (2002)
Code of Federal Regulations: Containing a Codification of Documents of General Applicability and Future Effect as of December 31, 1948, with Ancillaries and Index (2005)

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