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Key Documents

SCP0229

Sigma-Aldrich

Protein Tyrosine Phosphatase Substrate

≥95% (HPLC), lyophilized

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About This Item

Empirical Formula (Hill Notation):
C59H77N16O25
Molecular Weight:
1410.33
UNSPSC Code:
12352202
NACRES:
NA.32

product name

Protein Tyrosine Phosphatase Substrate,

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥85%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-DNP-Lys-Arg-NH2

Application

Protein Tyrosine Phosphatase Substrate (MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-DNP-Lys-Arg-NH2) may be used to identify and differentiate protein tyrosine phosphatases.

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Oliver Klein et al.
Scientific reports, 10(1), 15522-15522 (2020-09-25)
Enzymes are fundamental to biological processes and involved in most pathologies. Here we demonstrate the concept of simultaneously mapping multiple enzyme activities (EA) by applying enzyme substrate libraries to tissue sections and analyzing their conversion by matrix-assisted laser desorption/ionization (MALDI)

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