840635P

12:0 PA

1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt), powder

• Synonym(s): 1,2-didodecanoyl-sn-glycero-3-phosphate (sodium salt); DLPA; PA(12:0/12:0)
• Empirical Formula (Hill Notation): C₂₇H₅₂O₈PNa
• CAS Number: 108321-06-8
• Molecular Weight: 558.66
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 200 mg (840635P-200mg); pkg of 1 × 25 mg (840635P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 840635P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O)=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C27H53O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-26(28)33-23-25(24-34-36(30,31)32)35-27(29)22-20-18-16-14-12-10-8-6-4-2;/h25H,3-24H2,1-2H3,(H2,30,31,32);/q;+1/p-1/t25-;/m1./s1
• InChI key: CIOHBYXGWWPOIS-VQIWEWKSSA-M

Description

General description

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate) is a sodium salt of modified lipid, wherein C-1, C-2 of glycerol is substituted with didodecanoyl and C-3 of glycerol is substituted with phosphatidic acid group.

Application

12:0 PA (1,2-dilauroyl-sn-glycero-3-phosphate (sodium salt)) has been used as an internal lipid standard in the matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis. It may be used as a lipid standard:

• for the quantification of phospholipids by high-performance liquid chromatography coupled to tandem mass spectrometryelectrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
• for the quantification of lipids in cold-pressed rapeseed oils based on direct infusion electrospray ionization tandem mass spectrometry
• in liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis

Biochem/physiol Actions

Phosphatidic acid (PA) might serve as a modulator of phagocyte respiratory burst.

Packaging

5 mL Amber Glass Screw Cap Vial (840635P-200mg)

5 mL Amber Glass Screw Cap Vial (840635P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable