14-919-M
LRRK2 Protein, active, 10 µg
Active, N-terminal FLAG-tagged, recombinant, human LRRK2, amino acids 970-end. For use in Kinase Assays.
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Pricing and availability is not currently available.
Recommended Products
biological source
human
Quality Level
100
300
recombinant
expressed in baculovirus infected Sf21 cells
mol wt
Mw 180 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
GenBank accession no.
UniProt accession no.
Gene Information
human ... LRRK2(120892)
General description
Product Source: N-terminal FLAG-tagged, recombinant, human LRRK2 amino acids 970-end, expressed by baculovirus in Sf21 insect cells.
This protein is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Packaging
Also available in 250μg size as catalog # 14-919M and in bulk as catalog # 14-919-K.
Quality
Routinely evaluated by phosphorylation of ERMtide (RLGRDKYKTLRQIRQ)
Physical form
50mM Tris/HCl pH7.4, 300mM NaCl, 20mM β-glycerophosphate, 0.25mM sodium orthovanadate, 10mM NaF, 150µg/ml FLAG peptide, 20% v/v glycerol, 1mM benzamidine, 0.2mM PMSF, 5mM DTT. Frozen solution.
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
