Skip to Content
Merck

1.03796

SAFC

Cellvento® 4Feed COMP

chemically defined cell culture feed

Pharma Manufacturing

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41106213
Pricing and availability is not currently available.

Quality Level

description

shipped with cooling packs

product line

Cellvento®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

storage temp.

2-8°C

General description

Cellvento® 4Feed is a chemically defined feed formulation comprising components of non-animal origin. The product is useful for the development and manufacturing of biotherapeutics in Chinese hamster ovary (CHO) cell-based expression systems. Cellvento 4Feed is a highly concentrated, neutral pH feed that replenishes depleted nutrients required for cellular function. It maintains and extends the production phase in fed-batch mode. Cellvento 4Feed contains cysteine and tyrosine derivatives which release free cysteine and free tyrosine slowly throughout the culture. This is often related to higher cell growth and productivity. Cellvento 4Feed COMP is the feed format in compacted dry powder.

Application

Cellvento® 4Feed has been designed to support optimal cell growth and performance of chinese hamster ovary (CHO) suspension cell types and other CHO cell lines. It has also been used as a companion feed supplement with the production medium Cellvento CHO in fed-batch manufacturing processes.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

Free of charge - Sign in to download

Quality Management Dossier (Open Access)

Free of charge - Sign in to download

Operational Excellence Dossier

Available by subscription or for a fee

Learn more about the benefits an Emprove® Program subscription can provide
Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Optimizing feed for upstream cell culture improves monoclonal antibody production, but requires balancing outcomes for both viable cell density and productivity.

Why optimize your upstream bioprocess media and feed? This article discusses the why and how of optimizing your media and feed to maximize cell viability and productivity.

Our step-by-step guide to optimizing media and feed combinations for upstream bioprocessing.

This page describes the financial and operational advantages offered by the Cellicon® Cell Retention Device in an N-1 perfusion process at the 2,000 L scale in comparison to a cell retention device from another supplier.

See All

Related Content

Eliminate the need to clean, autoclave and assemble your traditional glass bioreactors and save days of downtime with the Mobius® 3L Single-use Bioreactor.

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

This page summarizes key considerations related to regulatory expectations for biomanufacturing including chemicals and polymeric materials. For chemicals, topics include nitrosamines and elemental impurities, and for polymeric materials such as filters and single-use assemblies, the focus is qualification and extractable and leachable testing.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service