- T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.
T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.
Nature communications (2017-11-28)
Iria Gomez-Tourino, Yogesh Kamra, Roman Baptista, Anna Lorenc, Mark Peakman
PMID29176645
ABSTRACT
Defects in T cell receptor (TCR) repertoire are proposed to predispose to autoimmunity. Here we show, by analyzing >2 × 10