- IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8
IL-12 stimulates CTLs to secrete exosomes capable of activating bystander CD8
Scientific reports (2017-10-19)
Lei Li, Steven M Jay, Yan Wang, Shu-Wei Wu, Zhengguo Xiao
PMID29042682
ABSTRACT
An effective cytotoxic T lymphocyte (CTL) response against intracellular pathogens is generally accomplished by immense CTL expansion and activation, which can destroy infected cells. Vigorous immune responses can lead to activation of bystander CD8
MATERIALS