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  • Record Broken: A Copper Peroxide Complex with Enhanced Stability and Faster Hydroxylation Catalysis.

Record Broken: A Copper Peroxide Complex with Enhanced Stability and Faster Hydroxylation Catalysis.

Chemistry (Weinheim an der Bergstrasse, Germany) (2017-04-21)
Patricia Liebhäuser, Kristina Keisers, Alexander Hoffmann, Thomas Schnappinger, Isabella Sommer, Anne Thoma, Claudia Wilfer, Roland Schoch, Kai Stührenberg, Matthias Bauer, Maximilian Dürr, Ivana Ivanović-Burmazović, Sonja Herres-Pawlis
PMID28425134
ABSTRACT

Tyrosinase model systems pinpoint pathways to translating Nature's synthetic abilities for useful synthetic catalysts. Mostly, they use N-donor ligands which mimic the histidine residues coordinating the two copper centres. Copper complexes with bis(pyrazolyl)methanes with pyridinyl or imidazolyl moieties are already reported as excellent tyrosinase models. Substitution of the pyridinyl donor results in the new ligand HC(3-tBuPz)