Inflammation-associated gene expression in RAW 264.7 macrophages induced by toxins from fungi common on damp building materials.

Inflammation-associated gene expression in RAW 264.7 macrophages induced by toxins from fungi common on damp building materials.

Toxicology in vitro : an international journal published in association with BIBRA (2017-05-26)

Thomas G Rand, Carolyn T Chang, David R McMullin, J David Miller

ABSTRACT

Most fungi that grow on damp building materials produce low molecular weight compounds, some of which are known to be toxic. In this study, we tested the hypothesis that exposure to some metabolites of fungi common on damp building materials would result in time-, dose-, and compound-specific responses in the production of various chemokines by RAW 264.7 cells. Cell cultures were exposed to a 10