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  • Synthesis of YF3: Yb, Er upconverting nanofluorophores using chitosan and their cytotoxicity in MCF-7 cells.

Synthesis of YF3: Yb, Er upconverting nanofluorophores using chitosan and their cytotoxicity in MCF-7 cells.

International journal of biological macromolecules (2014-12-03)
Sethuraman Gayathri, Oriparambil Sivaraman Nirmal Ghosh, Annamraju Kasi Viswanath, P Sudhakara, M Jeevan Kumar Reddy, A M Shanmugharaj
ABSTRACT

In this work, we described one pot hydrothermal synthesis of surface modified water soluble YF3: Yb, Er upconverting nanofluorophores (UCNFs) using natural biopolymer chitosan. The obtained nanocrystals have undergone X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), high resolution transmission electron microscopy (HRTEM) and photoluminescence (PL) studies. The nanoparticles possess uniform particle size distribution with average size about 27 nm. The cytotoxicity results revealed that the chitosan capped nanoparticles exhibit excellent biocompatibility in human breast cancer cells. In conclusion, the water soluble chitosan capped YF3: Yb, Er nanoparticles could be used as a potential candidate in bio-imaging and therapeutic applications.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Ytterbium, powder, ≥99.9% trace rare earth metals basis
Sigma-Aldrich
Ammonium fluoride, ≥99.99% trace metals basis
Ytterbium, foil, not light tested, 50x50mm, thickness 0.025mm, as rolled, 99%
Ytterbium, lump, 25g, max. size 25mm, 99.9%
Ytterbium, foil, not light tested, 25x25mm, thickness 0.005mm, as rolled, 99%
Ytterbium, rod, 50mm, diameter 6.35mm, cast, 99%
Ytterbium, lump, 100g, max. size 25mm, 99.9%
Ytterbium, foil, not light tested, 25x25mm, thickness 0.025mm, as rolled, 99%
Ytterbium, rod, 100mm, diameter 6.35mm, cast, 99%
Ytterbium, lump, 50g, max. size 25mm, 99.9%
Ytterbium, rod, 50mm, diameter 10.0mm, cast, 99%
Ytterbium, rod, 50mm, diameter 2.0mm, cast, 99%
Sigma-Aldrich
Yttrium(III) chloride, anhydrous, powder, 99.99% trace metals basis
Sigma-Aldrich
Ethyl alcohol, Pure, 200 proof, anhydrous, ≥99.5%
Sigma-Aldrich
Ethyl alcohol, Pure, 190 proof, ACS spectrophotometric grade, 95.0%
Sigma-Aldrich
Yttrium(III) chloride, AnhydroBeads, −10 mesh, 99.99% trace metals basis
Erbium, rod, 100mm, diameter 6.35mm, cast, 99%
Erbium, foil, 25x25mm, thickness 0.125mm, as rolled, 99%
Erbium, rod, 50mm, diameter 10.0mm, cast, 99%
Erbium, rod, 50mm, diameter 2.0mm, cast, 99%
Erbium, rod, 50mm, diameter 6.35mm, cast, 99%
Erbium, wire reel, 100mm, diameter 1.0mm, hard, 99.9%
Erbium, wire reel, 50mm, diameter 1.0mm, hard, 99.9%
Erbium, foil, not light tested, 25x25mm, thickness 0.005mm, as rolled, 99%
Erbium, foil, 50x50mm, thickness 1.0mm, as rolled, 99%
Erbium, foil, not light tested, 50x50mm, thickness 0.025mm, as rolled, 99%
Erbium, rod, 100mm, diameter 10.0mm, cast, 99%
Sigma-Aldrich
Ethyl alcohol, Pure, 160 proof, Excise Tax-free, Permit for use required