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Merck

An overview of the safety of sucralose.

Regulatory toxicology and pharmacology : RTP (2009-05-26)
V Lee Grotz, Ian C Munro
ABSTRACT

Sucralose is a non-nutritive sweetener used in a broad range of foods and beverages and is the non-nutritive sweetener in retail SPLENDA Sweetening Products, composed of sucralose and common food ingredients. A review of the extensive body of evidence that supports the safety of sucralose is provided. The results of an independent review of a new study investigating the safety of a sucralose-mixture retail product, Granulated SPLENDA No Calorie Sweetener, are also discussed. The collective evidence supports the conclusion that the ingredient, sucralose, is safe for use in food and that the sucralose-mixture product, Granulated SPLENDA No Calorie Sweetener, is also safe for its intended use.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Sucralose, ≥98.0% (HPLC)
Sucralose, European Pharmacopoeia (EP) Reference Standard
Supelco
Sucralose, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Sucralose, analytical standard