sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

GF20349435

Nickel, foil, not light tested, 50x50mm, thickness 0.005mm, as rolled, 99.9%

GF23635111

Nickel, insulated wire, 5m, conductor diameter 0.025mm, insulation thickness 0.0035mm, polyimide insulation

GF53163424

Nickel, foil, not light tested, 100x100mm, thickness 0.01mm, 99.95%

GF21421268

Nickel, mesh, 60x60mm, nominal aperture 0.43mm, thickness 0.004mm, wire diameter 0.067mm, 51 wires/inch, open area 75%, electro-formed mesh, 99.9%

GF11350381

Nickel, pellets, 100g, max. size 20mm, 99.99+%

GF04391591

Nickel, mesh, 100x250mm, nominal aperture 0.73mm, wire diameter 0.25mm, 26x26 wires/inch, open area 55%, plain weave mesh, 99%

GF10085240

Nickel, pellets, 20g, max. size 10mm, 99.99+%

GF35122092

Nickel, mesh, 65x65mm, nominal aperture 0.04mm, thickness 0.004mm, wire diameter 0.011mm, 500 wires/inch, open area 60%, electro-formed mesh, 99.9%

GF90261547

Nickel, mesh, 130x130mm, nominal aperture 0.04mm, thickness 0.004mm, wire diameter 0.011mm, 500 wires/inch, open area 60%, electro-formed mesh, 99.9%

GF40564144

Nickel, pellets, 20g, max. size 15mm, 99.99+%

GF56791378

Nickel, pellets, 100g, max. size 10mm, 99.999%

GF14407927

Nickel, pellets, 100g, max. size 15mm, 99.99+%

GF17897596

Nickel, pellets, 100g, max. size 5mm, 99.99+%

GF51346346

Nickel, foil, 100x100mm, thickness 0.125mm, annealed, 99.98%

GF73290089

Nickel, broken cathode squares, 1000g, max. size 50mm, 99.8%

GF20307620

Nickel, broken cathode squares, 100g, max. size 50mm, 99.8%

GF33783677

Nickel, broken cathode squares, 2000g, max. size 50mm, 99.8%

GF95981383

Nickel, broken cathode squares, 500g, max. size 50mm, 99.8%

GF64122094

Nickel, wire reel, 250m, diameter 0.125mm, as drawn, 99%

GF64264181

Nickel, foil, light tested, 50x50mm, thickness 0.05mm, as rolled, 99.98%

GF22812634

Nickel, insulated wire, 10m, conductor diameter 0.025mm, insulation thickness 0.0035mm, polyimide insulation

GF81996014

Nickel, pellets, 100g, max. size 10mm, 99.99+%

GF19857864

Nickel, insulated wire, 2m, conductor diameter 0.025mm, insulation thickness 0.0035mm, polyimide insulation

GF01449053

Nickel, pellets, 50g, max. size 15mm, 99.99+%

GF88419695

Nickel, insulated wire, 50m, conductor diameter 0.025mm, insulation thickness 0.0035mm, polyimide insulation