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H9627

Sigma-Aldrich

Hematoxylin

Synonym(s):

Natural Black 1

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About This Item

Empirical Formula (Hill Notation):
C16H14O6 · xH2O
CAS Number:
517-28-2
Molecular Weight:
302.28 (anhydrous basis)
Colour Index Number:
75290
Beilstein:
91400
EC Number:
208-237-3
MDL number:
MFCD00078111
UNSPSC Code:
12352204
PubChem Substance ID:
57654281
NACRES:
NA.32

form

powder

technique(s)

titration: suitable

mp

200 °C (dec.) (lit.)

solubility

95% ethanol: 1 mg/mL

SMILES string

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

InChI key

WZUVPPKBWHMQCE-XJKSGUPXSA-N

Gene Information

rat ... Adora1(29290) , Adora2a(25369)

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Application

Hematoxylin has been used for staining gastric cancer tissues, myocardial tissue, heart sections and ovarian nuclei.

Biochem/physiol Actions

Hematoxylin is an organic stain which chelates with metal ions and binds to DNA and RNA. It is used for staining nucleus of the cells. Hematoxylin along with eosin stain is used in the diagnosis of invasion stage in tumors.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hematoxylin and eosin staining of intact tissues via delipidation and ultrasound
Li Y, et al.
Scientific Reports, 8(1), 12259-12259 (2018)
Down-regulation of miR-327 alleviates ischemia/reperfusion-induced myocardial damage by targeting RP105
Yang Y, et al.
Cellular Physiology and Biochemistry, 49(3), 1049-1063 (2018)
A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy
Liu GS, et al.
Journal of Cellular and Molecular Medicine (2018)
In Situ Molecular Pathology and Co-Expression Analyses, 81-131 (2013)
Clinical significance and effect of Sam68 expression in gastric cancer
Xiao J, et al.
Oncology Letters, 15(4), 4745-4752 (2018)
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