MAB1580
Anti-Oligodendrocytes Antibody, clone NS-1
ascites fluid, clone NS-1, Chemicon®
Synonym(s):
RIP
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Pricing and availability is not currently available.
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biological source
mouse
Quality Level
antibody form
ascites fluid
antibody product type
primary antibodies
clone
NS-1, monoclonal
species reactivity
human, hamster, rat, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
isotype
IgG
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... OLIG2(10215)
Specificity
Recognizes Oligodendrocytes and their myelin sheaths. MAB1580 stains both early and mature oligodendrocites.
Immunogen
Rat olfactory bulb
Application
Detect Oligodendrocytes using this Anti-Oligodendrocytes Antibody, clone NS-1 validated for use in IC, IH.
Immunohistochemistry: 1:1000-1:200,000 on 4% paraformaldehyde fixed tissue.
Immunocytochemistry
Optimal working dilutions must be determined by the end user.
Immunocytochemistry
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Physical form
Liquid with 0.1% sodium azide.
Unpurified
Storage and Stability
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Oligodendrocyte culture, Brain
Oligodendrocyte culture, Brain
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Nathan VanderVeen et al.
Human gene therapy methods, 27(3), 98-111 (2016-04-09)
Glioblastoma multiforme (GBM) is the most commonly occurring primary brain cancer in adults, in whom its highly infiltrative cells prevent total surgical resection, often leading to tumor recurrence and patient death. Our group has discovered a gene therapy approach for
David Kaul et al.
PloS one, 7(5), e37767-e37767 (2012-06-06)
Toll-like receptors (TLR) are key players of the innate and adaptive immune response in vertebrates. The original protein Toll in Drosophila melanogaster regulates both host defense and morphogenesis during development. Making use of real-time PCR, in situ hybridization, and immunohistochemistry
Naomi L Sayre et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37(2), 514-527 (2016-02-14)
We previously demonstrated that stimulation of astrocyte mitochondrial ATP production via P2Y1 receptor agonists was neuroprotective after cerebral ischemic stroke. Another mechanism that increases ATP production is fatty acid oxidation (FAO). We show that in primary human astrocytes, FAO and
Xavier d'Anglemont de Tassigny et al.
Hypoxia (Auckland, N.Z.), 3, 15-33 (2015-06-08)
Chronic hypoxemia, as evidenced in de-acclimatized high-altitude residents or in patients with chronic obstructive respiratory disorders, is a common medical condition that can produce serious neurological alterations. However, the pathogenesis of this phenomenon is unknown. We have found that adult
Hua Jia Diao et al.
Journal of controlled release : official journal of the Controlled Release Society, 208, 85-92 (2015-03-10)
Remyelination in the central nervous system (CNS) is critical in the treatment of many neural pathological conditions. Unfortunately, the ability to direct and enhance oligodendrocyte (OL) differentiation and maturation remains limited. It is known that microenvironmental signals, such as substrate
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