PDK1
pyruvate dehydrogenase kinase, isozyme 1
Synonyms:
Species:
Human PDK1 (5163), Mouse Pdk1 (228026), Rat Pdk1 (116551), fruit fly Pdk1 (38017), Zebrafish pdk1 (555840), Thale Cress PDK1 (830330), Horse PDK1 (100064091), domestic guinea pig Pdk1 (100715937), naked mole-rat Pdk1 (101705587), sheep PDK1 (101113205) ...More
UniProtKB ID:
Gene ID:
- Human(5163) Summary: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
- Mouse(228026) pyruvate dehydrogenase kinase, isoenzyme 1
- Rat(116551) pyruvate dehydrogenase kinase, isozyme 1
- fruit fly(38017) Phosphoinositide-dependent kinase 1
- Zebrafish(555840) pyruvate dehydrogenase kinase, isozyme 1
- Thale Cress(830330) 3'-phosphoinositide-dependent protein kinase 1
- Horse(100064091) pyruvate dehydrogenase kinase, isozyme 1
- domestic guinea pig(100715937) pyruvate dehydrogenase kinase, isozyme 1
- naked mole-rat(101705587) pyruvate dehydrogenase kinase, isozyme 1
- sheep(101113205) pyruvate dehydrogenase kinase, isozyme 1
- Domestic Rabbit(100351323) pyruvate dehydrogenase kinase, isozyme 1
- cow(528655) pyruvate dehydrogenase kinase, isozyme 1
- domestic cat(101092705) pyruvate dehydrogenase kinase, isozyme 1
- dog(476828) pyruvate dehydrogenase kinase, isozyme 1
- chicken(425972) pyruvate dehydrogenase kinase, isozyme 1
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Small Molecule - Activator
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PDK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-PDK1 antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-PDK1/PDHK1 Antibody, clone 5T6S8, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-PDH kinase 1 Antibody, clone 1C7-H1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PDHK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human